The Scientist

Model Liver

The paper S. Hoehme et al., “Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration,” PNAS, 107:10371-76, 2010. Free ...
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Construction of region-specific liver organoid and fabrication of hierarchical functional liver lobule for liver disease modeling and drug evaluation

The central vein (CV) region, driven by the Wnt signaling pathway, and the portal vein (PV) region, driven by the Notch signaling pathway, enable us to construct a biomimetic liver lobule ...
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Human liver tissue cell architecture reconstructed in 3D at a cellular level

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...
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TOC: Construction of Region-Specific Liver Organoid and Fabrication of Hierarchical Functional Liver Lobule for Liver Disease Modeling and Drug Evaluation (IMAGE)

The central vein (CV) region, driven by the Wnt signaling pathway, and the portal vein (PV) region, driven by the Notch signaling pathway, enable us to construct a biomimetic liver lobule ...