Medscape

FDA Adds Warning to Osteoporosis Drug for Hypocalcemia Risk

The US Food and Drug Administration (FDA) has added a boxed warning to the label of the osteoporosis drug denosumab (Prolia) about increased risk for severe hypocalcemia in patients with advanced ...
Healio

FDA adds boxed warning of increased severe hypocalcemia risk for denosumab

Please provide your email address to receive an email when new articles are posted on . The FDA issued a boxed warning stating denosumab increases severe hypocalcemia risk for adults with advanced CKD ...
Healio

Older women with CKD on denosumab may have a higher risk for hypocalcemia

Please provide your email address to receive an email when new articles are posted on . Hypocalcemia risk increased with worsening CKD stages, particularly for patients on dialysis. Emergently treated ...
Medscape

Admission Ionized Hypocalcemia Found in 15% of Pediatric Major Trauma Cases

TOPLINE: Ionized hypocalcemia is seen in at least one in six pediatric patients with major trauma admitted to the emergency department (ED). Researchers performed a meta-analysis of three studies to ...
Monthly Prescribing Reference

Risk for Emergently Treated Hypocalcemia With Denosumab Rises With CKD Stage

The researchers found that with denosumab vs oral bisphosphonates, the risk for emergently treated hypocalcemia increased with worsening CKD stage. (HealthDay News) — For patients with chronic kidney ...
ascopubs.org

External Validation and Update of the Risk Prediction Model for Denosumab-Induced Hypocalcemia Developed From a Hospital-Based Administrative Database

Real-World Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With First-Line Nivolumab Plus Ipilimumab in the United States Denosumab is widely used in the treatment of bone metastases ...
Renal & Urology News

Denosumab vs Bisphosphonate Use Ups Emergency Hypocalcemia Risk in Advanced CKD

Worsening CKD was progressively associated with denosumab-induced hypocalcemia warranting emergency treatment. Denosumab use carries a higher risk for emergency hypocalcemia compared with ...
Monthly Prescribing Reference

FDA Adds Boxed Warning to Prolia Label Regarding Hypocalcemia Risk in CKD

Findings showed treatment with Prolia significantly increased the risk of developing severe hypocalcemia compared with bisphosphonates, especially in patients with advanced CKD. In patients with ...
Medical Xpress

Nutritional and Metabolic Diseases: News and Research on Hypocalcemia

A new study conducted across five U.K. air ambulance services has revealed significant variation in calcium levels among trauma patients receiving pre-hospital blood transfusions—highlighting a ...
The New England Journal of Medicine

Efficacy and Safety of Encaleret in Autosomal Dominant Hypocalcemia Type 1

Encaleret corrected hypocalcemia and reduced hypercalciuria during the inpatient periods and the 24-week outpatient period. Mean blood levels of intact PTH, magnesium, and 1,25-dihydroxyvitamin D ...
ascopubs.org

Incidence, factors enabling to predict and management of hypocalcemia following total thyroidectomy for thyroid cancer: A prospective observational study.

Progressive locally advanced or metastatic radioiodine-refractory differentiated thyroid cancer (RAI-R DTC) patients treated with donafenib: A real world study. This is an ASCO Meeting Abstract from ...